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Supplement Comparison Hub: What’s Worth Considering for Healthy Blood Pressure

Educational only. This hub summarizes randomized trials and high-quality reviews. It does not diagnose, treat, or replace medical care. Always discuss supplements with your clinician.

How we score

  • Promising: multiple randomized trials or meta-analyses show small average BP changes; heterogeneity is common.
  • Preliminary: limited trials or mixed results; more research needed.
  • Typical effect (avg): directional guidance (e.g., “small ≈ a few mmHg”); individuals vary.

For accurate tracking, use our guide: How to Measure & Track at Home. Pair any supplement with the fundamentals: Diet & Lifestyle for Healthy Blood Pressure.


Herbs & Teas

Supplement Evidence tier Typical effect (avg) Studied form & context Key safety notes Good fit (examples) Read full review
Hibiscus tea Promising Small–Modest (often clearer in elevated BP) 2–3 cups/day or standardized extracts over 4–8+ weeks Additive BP-lowering with meds; avoid if advised to restrict high-acid teas Adults who tolerate herbal teas and want a food-first adjunct Read full review
Garlic Promising Small–Modest (form- and dose-dependent) Aged garlic extract or standardized preparations; 8–12+ weeks Antiplatelet cautions (warfarin/antiplatelets); possible GI upset & odor Adults who can safely use allium supplements under clinician guidance Read full review

Nutrients

Supplement Evidence tier Typical effect (avg) Studied form & context Key safety notes Good fit (examples) Read full review
Omega-3 (EPA/DHA) Promising Small (often clearer at ~2–3 g/day combined) Fish or algal oil delivering combined EPA+DHA; weeks to months Anticoagulant/antiplatelet caution; fishy aftertaste; adjunct only Adults already improving diet who want a measured, clinician-coordinated trial Read full review
CoQ10 (Coenzyme Q10) Promising Small–Modest Ubiquinone/ubiquinol; 100–200 mg/day for 8–12+ weeks Possible interaction with warfarin; adjunct only Adults preferring a measured adjunct with core lifestyle work Read full review
Cocoa flavanols Promising Small (~2–3 mmHg in short-term trials) High-flavanol cocoa/extracts; endothelial function support Contains caffeine/theobromine; choose low-sugar options Food-first adjunct; pair with tracking & diet changes Read full review
Magnesium (citrate or glycinate) Promising Small (≈2/≈1–2 mmHg avg in meta-analyses) Elemental 200–400 mg/day; 8–12+ weeks Separate from certain antibiotics, bisphosphonates, levothyroxine; monitor with diuretics/PPIs Adults with low magnesium intake; clinician-coordinated Read full review
L-citrulline (vs. L-arginine) Preliminary → Promising Small (SBP ≈−4 mmHg avg; DBP signal at ≥6 g/day) 3–6 g/day for 2–8+ weeks Additive BP-lowering; caution with nitrates or PDE-5 inhibitors Adults already improving diet/activity who want an NO-pathway trial Read full review
Potassium (food-first) Promising (dietary) Modest via diet for many Beans, potatoes, greens, tomatoes, citrus, dairy; supplements clinician-only Do not self-supplement with CKD or on ACEi/ARB or K-sparing diuretics Most adults via diet changes; supplements only when prescribed/monitored Read full review
Taurine Promising Small–Modest (signals in prehypertension/cardiometabolic groups) ~1.5–3 g/day, typically 8–12 weeks Possible additive BP-lowering; avoid energy-drink combos Adults seeking an amino-acid adjunct with tracking & clinician input Read full review
Grape Seed Extract (OPCs) Promising Small–Modest (pooled SBP/DBP reductions) Standardized OPCs ~150–300 mg/day; 8–12+ weeks Antiplatelet/anticoagulant caution; choose reputable brands Adults who tolerate polyphenols and want a food-adjacent option Read full review
Probiotics (specific strains) Promising Small (more consistent at ≥1010 CFU; ≥8–10 weeks) Multi-strain products 8–10 weeks; diet quality matters Immunocompromised: consult clinician first Adults improving diet & fiber intake who want a microbiome adjunct Read full review
Psyllium (soluble fiber) Promising Small SBP decrease (meta-analyses) 7–10 g/day with water; space from meds by 2+ hours Must take with adequate fluids; start low/titrate Adults targeting BP + LDL + glycemia with one habit Read full review
Vitamin C Preliminary → Promising Small (signals in hypertensive adults) ~500–1,000 mg/day; 8–12 weeks Kidney-stone caution in some men at high doses; UL 2,000 mg/day Adults wanting a low-cost trial under clinician guidance Read full review
Green Tea Catechins Preliminary Small (~2 mmHg; mixed results) 2–4 cups tea or extracts providing catechins/EGCG; 8–12 weeks Caffeine sensitivity; rare liver issues with high-dose extracts—take with food Tea-friendly routines; consider decaf options if sensitive Read full review
L-Arginine Promising Small–Modest (dose-response meta) ~4–6 g/day; 2–8+ weeks; compare with L-citrulline Additive BP-lowering; PDE-5/nitrate cautions; avoid after recent MI unless supervised Adults already improving diet/activity who want an NO-pathway trial Read full review

Nitrate-Rich Foods

Food / supplement Evidence tier Typical effect (avg) Studied form & context Key safety notes Good fit (examples) Read full review
Beetroot / beet juice (dietary nitrate) Promising Small (often −3 to −5 mmHg SBP) ~250 mL juice/day or ~300–600 mg nitrate; daily intake High oxalate; caution with kidney stone history; antiseptic mouthwash may blunt effect Adults who tolerate beets and want a food-first option with tracking Read full review

Important: Supplements are optional and work best alongside diet & lifestyle, accurate home tracking, and clinician-directed care. This page is educational and not medical advice.

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